Sending Cold Email From SimpleSend: Domains, Warmup, Pacing and One Reply Inbox

How SimpleSend sends cold email: lookalike domains in your name, automatic warmup, conservative pacing, pre-flight checks and one inbox for every reply.

SS
SimpleSend Labs
Field notes from the research team
READ12 minWORDS2,000UPDATEDOct 2, 2026

SimpleSend can now send the sequences it drafts. You pick sending domains and mailboxes in the app; SimpleSend registers, authenticates and warms them, paces your sequence conservatively, and puts every reply in one inbox. Here is each part, including what it holds back and what it costs.

One rule sits under all of it. Send cold email from dedicated, authenticated domains, never your main one, and warm them first. That is true whether you send from SimpleSend, Smartlead or Instantly. The difference here is that the setup is done for you. For a tour of the screens, see the Email Sequences page.

Domains in your nameDNS publishedMailboxes warmedSequence launchedReplies in one inbox

Why cold email goes out from separate domains

Your main domain carries your company's everyday email: invoices, support threads, replies to investors. Mailbox providers judge every domain by how its mail is received, and cold outreach, even good cold outreach, draws more ignores, deletes and the occasional spam complaint than ordinary business mail. Put that volume on your main domain and one bad week can follow your whole team into the spam folder.

A lookalike domain limits the blast radius. If you own acme.com, you send cold email from something like getacme.com or tryacme.com, with a few mailboxes on each. Visitors to the lookalike land on your real site, replies come back to mailboxes you control, and if a domain's reputation slips, you retire it without touching the address your customers use.

The other half is authentication. Google and Yahoo require bulk senders to publish SPF, DKIM and DMARC, and Microsoft brought in similar rules for high-volume mail to Outlook.com addresses in 2025. Unauthenticated cold email is increasingly filtered or rejected before anyone sees it.

What SimpleSend sets up for you

Everything lives in the Sequences section of the app, alongside Domains, Mailboxes and the Inbox. Most of the work is SimpleSend's:

PieceWhat SimpleSend doesYour part
DomainsRegisters lookalike domains in your name and redirects each one to your main websitePick the names
DNSPublishes SPF, DKIM and DMARC for every domain. DMARC starts on a monitoring policy (p=none) you can tighten later, and the Domains page shows a pass or fail for each recordNothing, unless a check fails
MailboxesCreates Google or Microsoft mailboxes, up to five per domain (three is the recommended number)Choose the sender names
WarmupStarts on its own when a mailbox is created and keeps running after it is readyWait two to three weeks
Signature and addressSends every email with the mailbox's signature and your business mailing address printed under itWrite a signature for each mailbox and add the address once, before your first launch

What SimpleSend does not do is send from an inbox you already use. Sending only from mailboxes created in the app keeps cold volume off your main domain, and keeps authentication, warmup and pacing consistent for every mailbox you send from.

Warmup: two to three weeks, handled for you

A brand-new mailbox has no history, and mailbox providers are wary of strangers. Warmup builds that history by sending and receiving a steady trickle of ordinary-looking email before any cold outreach goes out. In SimpleSend it starts automatically: about two weeks for Google mailboxes, about three for Microsoft. Each mailbox shows Warming until then, and Ready after.

Warmup keeps running after a mailbox turns Ready, which helps hold reputation steady while real volume goes out. Aged domains do help, but a new, fully authenticated domain with two to three weeks of warmup and a slow ramp is a sound start. Our Email Warmup and Domain Health guide goes deeper on reputation and how to monitor it.

Pacing: the defaults, and why they are low

Most deliverability trouble comes from sending too much, too fast, from too few mailboxes. SimpleSend's defaults are deliberately conservative, and the most important one has a ceiling you cannot raise.

SettingDefaultWhy
Send windowWeekdays, 8am to 5pm in each mailbox's time zoneBusiness email from a person arrives during business hours
Gap between sends4 to 9 minutes, randomized, per mailboxNo bursts that look like a machine
Daily sends per mailbox25. You can raise it to 40, and it never goes above 50Low volume per mailbox is the best protection a reputation has
New mailbox ramp10 a day in the first week of sending, 18 in the second, then your capTrust is earned gradually
New leads per sequence50 a day, with follow-ups on topFirst touches spread over days, not hours
Mailbox healthA mailbox whose health slips sends less, or pauses, until it recoversProblems slow down instead of compounding

Do the math before you launch. Three mailboxes at the default cap send up to 75 emails a day once ramped, enough for a focused list of a few hundred people on a four-step sequence. Need more? Add mailboxes and domains rather than pushing each one harder.

None of this guarantees inbox placement, and nothing can. It is designed to give every email its best chance. The rest comes down to a clean list and copy people want to read.

Turning drafts into a sequence

From a drafted campaign

When SimpleSend finishes drafting a campaign, the last screen offers Send with SimpleSend next to Download CSV. Choose it and the campaign becomes a sequence in which every lead keeps their own researched wording for every step. You pick the mailboxes, check the schedule and launch.

From the builder

You can also start a sequence blank or from a lead list and write shared steps yourself, with merge tags such as {{first_name}} and fallbacks such as {{company|your team}} for missing values. If a tag has no value and no fallback, that email stops rather than going out with a raw tag in it. The builder suits short announcements, or copy you already trust.

Either way, a sequence holds up to 10 steps, with delays of up to 60 days between them, and up to 5,000 leads. Follow-ups go out as replies in the same thread, the way a person follows up.

Pre-flight: what gets held back

Before anything sends, SimpleSend checks every lead and holds back the ones that would hurt your mailboxes or annoy someone. Held leads are listed with the reason, so you can fix them or leave them out:

  • Invalid addresses, domains that accept no mail, and system inboxes such as noreply@ or postmaster@
  • Catch-all domains, which accept every address and can bounce later (held unless you choose to allow them)
  • Anyone on your suppression list, and the same address listed twice
  • Leads already live in a teammate's sequence, so two people on your team never email the same person at once
  • Companies where someone replied to you in the last 90 days, so a cold email never cuts across a live conversation
  • Leads that are missing wording for a step

Send yourself a test to see each step exactly as a lead will. Sending also needs two things from you: a signature on every sending mailbox (set it on the Mailboxes page) and your business mailing address, which is printed under every signature.

Before you press launch
  • Every mailbox you picked shows Ready, not Warming
  • The Domains page shows a pass for SPF, DKIM and DMARC
  • Each sending mailbox has a signature, and your mailing address is set
  • A test email reads well on your phone
  • The held leads, and the reasons they were held, make sense

One inbox for every reply

Replies from every mailbox land in one Inbox in the Sequences section, and a reply stops that lead's follow-ups automatically. You can also stop on an open or a click, though opens are noisy.

Each reply gets a label so you can work the list in order of value: Interested, Wants a meeting, Has a question, Referral, Not now, Not interested, Asked to stop and Wrong person. Out-of-office replies and bounces are marked too, and an out-of-office pauses that lead instead of letting the next step land in an empty inbox.

Open a thread and Draft with AI writes two short replies from the conversation and your brief, ready to edit, and your answer goes out from the same mailbox and thread. Turn on reply alerts and SimpleSend emails you when someone writes back.

Unsubscribes, suppression and bounces

Every email SimpleSend sends carries three things: an opt-out line under the signature (by default, "Not the right person or not interested? Just reply and let me know."), an unsubscribe link, and your business mailing address. Saying no should take one line or one click, and it does.

When someone unsubscribes, asks you to stop, or hard-bounces, their address joins a suppression list shared by your whole team, and pre-flight holds it in every sequence from then on.

If bounces spike on a mailbox or a sequence, SimpleSend pauses it automatically, so a bad list cannot drag a mailbox's reputation down while you are not looking. Clean the list, then resume.

Tracking, without the bot noise

Open and click tracking are on by default, and you can turn either off for any sequence. Security scanners open mail automatically, which inflates open rates in most tools; SimpleSend filters out those machine opens. Each sequence reports sent, opened, clicked, replied, bounced and opted out. Treat replies as the number that matters. There is no built-in A/B test: to compare two angles, split the list into two sequences and compare reply rates once both have finished.

What it costs

Sending is included on Pro ($250/mo), with 1 sending domain and 3 warmed Google inboxes set up for you. Every Teams seat ($215/seat/mo, 3-seat minimum) includes 1 domain and 3 inboxes of its own. On Individual ($50/mo), add Email Sending for $49.99/mo and buy the domains and mailboxes you need at the standard rates, which also apply to extra domains and mailboxes on any plan.

Sending itself uses no credits; credits pay for research and drafting. The 14-day free trial covers research and drafting but not sending, so you can draft during the trial and send once you are on a paid plan.

Prefer your own sender?

Plenty of teams already run Smartlead or Instantly with warmed mailboxes they are happy with. That path stays open. Download the CSV instead of sending: it has stable columns such as step_1_subject and step_1_body for every step, ready to map into Smartlead, Instantly, Apollo, HubSpot, GoHighLevel or a Gmail mail-merge. Our CSV to Smartlead walkthrough shows the mapping step by step. The same rule applies there as here: dedicated, authenticated, warmed domains, never your main one.

Either way, the hard part (research, and writing that sounds like you) is done before the first email goes out. Sending from SimpleSend just removes the setup between a finished draft and a live sequence.

Frequently asked questions

Can I send from my existing Gmail or Outlook account?
No. SimpleSend sends only from mailboxes created in the app, on lookalike domains registered in your name, which keeps cold volume off your main domain. If you would rather use a sender you already run, export the CSV instead.
How long until a new mailbox can send cold email?
Warmup runs automatically for about two weeks on Google mailboxes and about three on Microsoft. After that, a new mailbox sends 10 emails a day in its first week of sending and 18 a day in its second, then moves to your daily cap, which is 25 by default.
How many cold emails can one mailbox send a day?
25 by default. You can raise a mailbox to 40, and SimpleSend never goes above 50. Three mailboxes at the default send up to 75 emails a day once they have ramped.

Sources and further reading: Google email sender guidelines; Yahoo sender best practices; running LinkedIn and email together. Defaults described here are SimpleSend's as of October 2026.

If you'd rather not assemble the research, voice-matching, and QA layers yourself, SimpleSend does all three. Start from a CSV, a HubSpot list or a Find Leads search: every contact gets fresh research, every draft is written in your voice from samples, and every email goes through the QA pass. Then send it from SimpleSend or export it to the sender you already use. Start with a 14-day free trial, no card; plans from $50/month.
TRY THE FRAMEWORK

Run your next campaign through SimpleSend.

Bring a CSV, a HubSpot list or Find Leads contacts, paste 1–3 of your past emails, and get every sequence drafted row by row. Then send it from your own SimpleSend mailboxes or export it to Smartlead, Instantly or your CRM. Start with a 14-day free trial, no card; plans from $50/month.

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